Endocrine Abstracts

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by inappropriate secretion of parathyroid hormone leading to hypercalcemia. The aim of our study is to evaluate the clinical and etiological aspects of PHPT in our series.Methods: This is a retrospective descriptive study including 32 patients followed for PHPT at the endocrinology department of the military hospital of Tunisia between January 2018 and December ...

Introduction: Surgery is the only curative treatment for primary hyperparathyroidism (PHPT). However, some patients may present a persistence or a recurrence after surgical treatment. The aim of our study was to evaluate the therapeutic and evolutive aspects of PHPT after the first surgery.Methods: A retrospective study was conducted at the endocrinology department of military hospital of Tunis including 32 patients diagnosed with PHPT over a period of f...

Introduction: Classification of diabetes is challenging in some cases, especially in the presence of inaugural ketosis with a negative autoimmune laboratory test. The aim of our study is to determine the role of age, body mass index (BMI), and fasting plasma C-peptide (FCP) in the classification of diabetes.Methods: This is a descriptive cross-sectional study that included 51 patients aged between 20 and 65 years hospitalized at the Endocrinology Departm...

Introduction: Papillary Thyroid Carcinoma (PTC) is the most frequent cancer of the thyroid. PTC may rarely coexist with Primary hyperparathyroidism (PHPT). Furthermore, the association of PTC and graves’ disease (GD) has been described and the existence of a link between these entities has long been investigated, but no clear correlation has been established. We report the case of a female patient who suffered from GD, PTC and PHPT.Observation: A 34...

Introduction: The majority of systemic diseases result from an autoimmune process. Primary adrenal insufficiency (Addisson’s disease AD) is also frequently caused by an autoimmune process. Their association is rare but can be seen in the framework of autoimmune polyendocrinopathies. We report 2 observations associating an autoimmune adrenal insufficiency with a systemic disease.Observation 1: We describe the case of a 50-year-old patient initially a...

Introduction: Papillary thyroid carcinoma is one of the most prevalent endocrine tumors. Adrenocorticotropic hormone (ACTH) dependent Cushing’s syndrome is a rare disease. We report a rare case of coexistence of papillary thyroid carcinoma and ACTH-dependent Cushing’s syndrome.Observation: A 59-year-old man, was admitted to our endocrinology department for exploration of bilateral adrenal incidentalomas discovered in an abdominal CT scan done i...

Introduction: Adrenal adenomas development has been partially explained by aberrant adrenal expression of some hormone receptors. Klinefelter’s syndrome is a common cause of hypergonadotropic hypogonadism, which is characterized by increased serum LH level. In this case, we report a patient with Klinefelter syndrome, who was later diagnosed with a non secreting adrenal adenoma.Case presentation: We report the case of a 57 years old patient, diagnose...

Introduction: Gilbert syndrome is a common autosomal dominant hereditary condition characterized by intermittent unconjugated hyperbilirubinemia in the absence of hepatocellular disease or hemolysis. Multiple endocrine neoplasia (MEN) is defined by the association of a neoplasia or hyperplasia of at least two endocrine glands and caused by multiple mutations. Rare cases of atypical MEN were reported in the literature. We report the case of a patient with a history of gilbert&#...

Introduction: Liraglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA), approved for management of type 2 diabetes (T2D).Aim: The aim of our study is to evaluate the effectiveness of Liraglutide in controlling blood glucose levels over a period of 6 to 12 months in Tunisian type 2 diabetic patients.Methods: We conducted a prospective descriptive study at the endocrinology-nutrition department of the military hospital of...

Introduction: Liraglutide has been shown to have a positive effect on the glycemic and lipidic profile of diabetic patients. We aimed to assess the metabolic profile in type 2 diabetic patients after 12 weeks of treatment by LiraglutideMethods: This is a prospective study performed at the endocrinology department of the Military Hospital of Tunis. We recruited 22 patients with type 2 diabetes (T2D) treated with insulin and/or oral antidiabetics. Liraglut...